Given my integrative approach to therapy and the fact that clients will have a say in the path we choose, I am often asked which approach is the best treatment for depression. The short answer is that each treatment course is uniquely designed depending on your needs, symptoms, and personality, but there are some approaches that I lean on to provide the best therapy for depression. Later in the post, I explain why the most effective treatment for depression may not be the best method for you.

Please feel free to contact me or schedule a consultation to get more information about how we can design the best treatment for depression for your unique needs.

Best Therapy for Depression: Your Choices

I have found several types of therapy to be particularly effective:

Cognitive Behavioral Therapy (CBT): Cornerstone Approach

Cognitive behavioral therapy is one of the most widely researched and effective therapies for depressive disorders. It focuses on identifying and challenging negative thought patterns and beliefs contributing to symptoms. Through CBT, you learn to replace negative thoughts with more realistic and positive ones, as well as develop coping strategies to manage your emotions and behaviors. Many therapists would say that if they had to choose one “best therapy for depression,” it would likely be CBT, but I still like to mix other effective methods in.

Behavioral activation is a component of many therapies in this area, including CBT. It involves scheduling and engaging in activities that bring pleasure and a sense of accomplishment, even when one doesn’t feel like it. By increasing activity levels and reintroducing enjoyable experiences into your life, you can disrupt the cycle of sadness and improve your mood. I use behavioral activation but only at a pace that you are comfortable with.

Interpersonal Therapy (IPT): Best Therapy for Depression with Social Roots

IPT is a short-term therapy that focuses on improving interpersonal relationships and communication skills. It helps you identify and address interpersonal issues contributing to your symptoms, such as conflicts with loved ones, grief, or social isolation. I find that IPT approaches make it to the best treatment for depression list when improving your social life and depth of social connections is high on your list.

Mindfulness-Based Therapies: Relapse Prevention

Therapies such as Mindfulness-Based Cognitive Therapy (MBCT) and Acceptance and Commitment Therapy (ACT) incorporate mindfulness techniques to help you develop greater awareness of your thoughts and emotions and learn to relate to them in a more accepting and compassionate way. These therapies can be particularly helpful for preventing relapse in recurrent depressive disorders.

These techniques are often best learned during treatment. After you reach your goals, it is helpful to continue practicing them to reduce the chances of relapse and maintain your mood.

Best Therapy for Depression that is Longstanding: Psychodynamic

Psychodynamic therapy focuses on exploring unconscious thoughts, feelings, and past experiences that may contribute to current difficulties. By gaining insight into the root causes of your sadness, you can develop a deeper understanding of yourself and make meaningful changes in your life. I tend to use psychodynamic approaches when depressive problems are longstanding, have not responded to CBT, or when there is a clear historical cause.

Ultimately, the best therapy for depression is one that feels like a good fit for you and addresses your specific needs and goals.

Best Treatment for Depression: Comprehensive Approaches

When a comprehensive approach is desired, the best treatment for depression can stretch beyond therapy, as depression is a complex condition with diverse underlying causes and manifestations. Some common approaches that can be combined with therapy include:

Medication: Best Treatment for Depression that is Severe

Antidepressant medications, such as SSRIs (Selective Serotonin Reuptake Inhibitors) or SNRIs (Serotonin and Norepinephrine Reuptake Inhibitors), are often prescribed to help regulate brain chemistry and alleviate symptoms. While for most people, any one or a combination of the best therapy for depression approaches listed above will be enough, more severe symptoms may require medication, at least for a while, to help you feel stable and strong.

Best Treatment for Depression Outside of Sessions: Lifestyle Changes

Engaging in regular exercise, maintaining a balanced diet, getting enough sleep, and avoiding alcohol and drugs can all contribute to improved mood and overall well-being. Establishing a routine and setting achievable goals can also be beneficial. Building and maintaining strong social connections can provide emotional support and reduce feelings of isolation. Spending time with friends and family or participating in support groups can offer validation, encouragement, and practical assistance.

Mindfulness and Relaxation Techniques

Practices such as mindfulness meditation, yoga, deep breathing exercises, and progressive muscle relaxation can help manage stress, reduce anxiety, and promote a sense of calm. Along with mindfulness, engaging in activities that bring joy, fulfillment, and a sense of accomplishment can improve mood and self-esteem. This might include hobbies, creative pursuits, spending time in nature, or volunteering.

Best Treatment for Depression Alternatives

Some individuals find relief from their symptoms through alternative or complementary therapies such as acupuncture and acupressure, massage therapy, or herbal supplements. I am always willing to talk to you to ensure that these approaches complement, rather than replace, conventional treatments. I will refer you to well-trained professionals in these areas who can guide you and let you know how each method fits well with the individual therapy I provide.

Most Effective Treatment for Depression

Many people want to look to numbers and data to understand the most effective treatment for depression. While this is certainly close to asking about the “best” treatment, the “most effective” treatment for depression would suggest that the therapy works particularly quickly, reduces the most symptoms, and keeps a person free of symptoms longer.

In my experience, the most effective treatment for depression may actually not be the “best” treatment. For example, an effective treatment for depression may require more frequent meetings than are feasible, may include treatment techniques that will cause discomfort, or may lower symptoms without getting to underlying causes. The most effective treatment for depression may be one that lowers the symptoms now but does not prevent relapse.

Instead of the Most Effective Treatment for Depression…

For the above reasons, I suggest that people look for the best therapy for depression for their unique needs, comfort, and depressive origins. If you want lasting and deep results from therapy, the best treatment may not be quite the most effective treatment for depression, but it may be the most lasting, deep, and comfortable course for you. Of course, in many cases, the most effective treatment for depression is also the best method!

Summary and My Work

An integrated approach that includes several different proven therapy methods and supplemental and adjunctive approaches often works best. I am happy to talk to you about what the best treatment for depression might be for you. We will develop a personalized treatment plan addressing your needs and circumstances. A combination of therapy, medication, and lifestyle changes may be most effective in severe cases.

Choosing the Best Treatment for Depression: Example

Here’s a fictitious example that is typical and shows how I might select the most effective treatment for depression for a client:

Jane is a 35-year-old woman experiencing her first major depressive episode. She has been feeling persistently sad, has lost interest in activities she used to enjoy, and has trouble sleeping and concentrating. Jane has no history of mental illness, but her mother had depression. Jane prefers to avoid medication if possible. I start with a comprehensive evaluation, including a detailed medical and psychological history. I use an empirical tool called the Patient Health Questionnaire-9 (PHQ-9) to gauge the severity of Jane’s depression. During this initial process, I also screen for other possible conditions, such as anxiety disorders, but there are no signs that this is a significant problem.

Some stress in her social life involving a relationship ending, some longstanding family issues, and challenges at work after a recent promotion may be causing her low mood.

Discussion of Treatment Options

Jane and I discussed various treatment options, and she felt that two of them resonated with her, and I agreed. For Jane, the best treatment for depression would combine two approaches:

  • Cognitive Behavioral Therapy (CBT): Given that she feels that her underlying thoughts relative to self-esteem, work competence, and her future outlook are causing her distress, it seems that CBT would be the most effective treatment for depression. We will use it to identify and change negative thought patterns and behaviors.
  • Interpersonal Therapy (IPT): We will also mix in IPT, which focuses on improving Jane’s interpersonal relationships, nurturance needs, and communication patterns, which might be contributing to her depression.
  • Sleep Hygiene: Tips for improving sleep patterns will also be provided, as sleep disturbances are a significant part of Jane’s depressive symptoms.

Outcomes

After six weeks of CBT sessions, Jane notices an improvement in her mood and a reduction in her depressive symptoms. IPT is also helping her address some of the root causes of her symptoms. We decided to meet twice monthly to assess the effectiveness of the treatment plan, including coping strategies, stress management methods, and CBT techniques, and make necessary adjustments.

The above is a general example of how I find the best therapy for depression for each client. The techniques chosen by Jane may not be the ones that work best for you, and that’s why I make sure you are fully informed about different possible approaches so we can work together to find the more effective course.


I provide this therapy mostly to individuals, but it can be a core component of couples therapy and family therapy as well. I also provide some specific services, such as CBT for Seasonal Depression.

Please feel free to contact me or schedule a consultation, and we can start to explore the best treatment for depression for your unique needs.

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Dr. Alan Jacobson Psychologist
Dr. Jacobson is a licensed clinical psychologist providing individual, couples, and family therapy for over 20 years. He uses an integrative approach. choosing from a variety of proven and powerful therapeutic methods.